Applied and fundamental research on Particle Technology
Particle technology, crucial in various industries for its role in influencing product quality and efficiency, presents significant challenges due to the complexities involved in particle characterization, manipulation, and processing, necessitating innovative approaches to address issues such as agglomeration, segregation, and granular rheology.
POWDER MECHANICS AND FLOWABILITY
- Physics and mechanics of granular flows:
- particular focus on dense flow regime
- modeling of the dense granular flows (FEM, DEM)
- Flowability characterization
- Hoppers optimization and design for flow
- Packing and compaction of particles
INTERACTIONS OF SOLIDS WITH FLUIDS
- Wet granulation (high-, low-shear):
- use of alternative binders/excipients
- Multiphase flows (gas-solid flows):
- permeability and tortuosity in packed beds
- Multiphase flows (wet granular materials):
- rheology of wet granular bulks
- Modeling of drying processes Reconstitution enhancement of dry powders
- Characterization of powder wettability
MIXING AND SEGREGATION IN GRANULAR MEDIA
- Mixing process and mechanisms
- Mixers scale-up
- Powder sampling
- Mixture quality evaluation
- Segregation mechanisms and mitigation
POWDER AND PARTICLE CHARACTERIZATION
- Image and texture analysis for:
- mixture quality evaluation
- particle size and shape analysis
- Powder sampling
- Flowability of powders
- Wettability
- Caking
- Permeability of packed beds
