{"id":482,"date":"2022-12-22T17:08:06","date_gmt":"2022-12-22T16:08:06","guid":{"rendered":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482"},"modified":"2023-01-27T12:10:48","modified_gmt":"2023-01-27T11:10:48","slug":"3d-bioprinting","status":"publish","type":"page","link":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482","title":{"rendered":"3D Bioprinting to mimic human body"},"content":{"rendered":"<p>3D bioprinting is an additive manufacturing process that involves the use of biomaterials, cells and biomolecules to fabricate three-dimensional structures that mimic the characteristics and function of specific natural tissues. The bioprinting process starts with modeling the three-dimensional constructs, creating a digital model equipped with a set of instructions for fabricating layer-by-layer the desired structure. Depending on the application, a biomaterial is mixed with cells to form a bioink and then is deposited on a printing plate following the instructions generated to fabricate the 3D model. In the BIAMET lab, this process is primarily used to produce vascularized tumor models for studying the premetastatic stage, and to create skin models to test the effect of drugs and cosmetics.<\/p>\n<p><strong>3D bioprinting for vascularized tissue fabrication<br \/>\n<\/strong><\/p>\n<p><span id=\"page3R_mcid5\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">3D<\/span> <span dir=\"ltr\" role=\"presentation\">cultures<\/span> <span dir=\"ltr\" role=\"presentation\">and<\/span> <span dir=\"ltr\" role=\"presentation\">cell<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">laden <\/span><span dir=\"ltr\" role=\"presentation\">hydrogel<\/span> <span dir=\"ltr\" role=\"presentation\">constructs<\/span> <span dir=\"ltr\" role=\"presentation\">are<\/span> <span dir=\"ltr\" role=\"presentation\">fundamental<\/span> <span dir=\"ltr\" role=\"presentation\">in<\/span> <span dir=\"ltr\" role=\"presentation\">biomedical <\/span><span dir=\"ltr\" role=\"presentation\">research<\/span> <span dir=\"ltr\" role=\"presentation\">as<\/span> <span dir=\"ltr\" role=\"presentation\">t<\/span><span dir=\"ltr\" role=\"presentation\">hey<\/span> <span dir=\"ltr\" role=\"presentation\">represent<\/span> <span dir=\"ltr\" role=\"presentation\">physiologically relevant models <\/span><span dir=\"ltr\" role=\"presentation\">provid<\/span><span dir=\"ltr\" role=\"presentation\">ing<\/span> <span dir=\"ltr\" role=\"presentation\">mechanistic cues to guide cell fate and function<\/span>. <span dir=\"ltr\" role=\"presentation\">In<\/span> <span dir=\"ltr\" role=\"presentation\">addition,<\/span> <span dir=\"ltr\" role=\"presentation\">advances<\/span> <span dir=\"ltr\" role=\"presentation\">in<\/span> <span dir=\"ltr\" role=\"presentation\">additive<\/span> <span dir=\"ltr\" role=\"presentation\">manufacturing <\/span><span dir=\"ltr\" role=\"presentation\">techniques, particularly 3D bioprinting, not only allow for <\/span><span dir=\"ltr\" role=\"presentation\">a precisely shaped construct, but also for the production of <\/span><span dir=\"ltr\" role=\"presentation\">patient<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">specific patches. The ability to recapitulate the <\/span><span dir=\"ltr\" role=\"presentation\">complexity of the<\/span> <span dir=\"ltr\" role=\"presentation\">in vivo<\/span> <span dir=\"ltr\" role=\"presentation\">milieu<\/span> <span dir=\"ltr\" role=\"presentation\">using 3D bioprin<\/span><span dir=\"ltr\" role=\"presentation\">ting is <\/span><span dir=\"ltr\" role=\"presentation\">particularly important for<\/span> <span dir=\"ltr\" role=\"presentation\">studies involving the<\/span> <span dir=\"ltr\" role=\"presentation\">role of the <\/span><span dir=\"ltr\" role=\"presentation\">tumor microenvironment (TME)<\/span> <span dir=\"ltr\" role=\"presentation\">in cancer<\/span><span dir=\"ltr\" role=\"presentation\">,<\/span> <span dir=\"ltr\" role=\"presentation\">improving <\/span><span dir=\"ltr\" role=\"presentation\">upon<\/span> <span dir=\"ltr\" role=\"presentation\">2D cultures or scaffold<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">free 3D culture strategies.<\/span><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">3D bioprint<\/span><span dir=\"ltr\" role=\"presentation\">ed<\/span> <span dir=\"ltr\" role=\"presentation\">tumor models are<\/span> <span dir=\"ltr\" role=\"presentation\">already being developed <\/span><span dir=\"ltr\" role=\"presentation\">in a variety of struc<\/span><span dir=\"ltr\" role=\"presentation\">tures ranging from slices, grids, fibers, <\/span><span dir=\"ltr\" role=\"presentation\">mini<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">organs, and custom shapes.<\/span> <span dir=\"ltr\" role=\"presentation\">However, t<\/span><span dir=\"ltr\" role=\"presentation\">o be <\/span><span dir=\"ltr\" role=\"presentation\">clinically relevant<\/span><span dir=\"ltr\" role=\"presentation\">,<\/span> <span dir=\"ltr\" role=\"presentation\">tissue constructs<\/span> <span dir=\"ltr\" role=\"presentation\">must<\/span> <span dir=\"ltr\" role=\"presentation\">be significantly <\/span><span dir=\"ltr\" role=\"presentation\">thicker than the few hundred microns where diffusion is <\/span><span dir=\"ltr\" role=\"presentation\">sufficient to provide nutrients to<\/span> <span dir=\"ltr\" role=\"presentation\">all culture<\/span><span dir=\"ltr\" role=\"presentation\">d<\/span> <span dir=\"ltr\" role=\"presentation\">cells.\u00a0 A <\/span><span dir=\"ltr\" role=\"presentation\">primary method for overcoming the hurdle of sustaining <\/span><span dir=\"ltr\" role=\"presentation\">cells in the bulk is to create a vascular network within these <\/span><span dir=\"ltr\" role=\"presentation\">cell<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">laden constructs.<\/span><\/span><span id=\"page3R_mcid6\" class=\"markedContent\"><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">BIAMET lab <\/span> <span dir=\"ltr\" role=\"presentation\">propose a fabrication method for vascularized 3D c<\/span><span dir=\"ltr\" role=\"presentation\">onstructs<\/span> <span dir=\"ltr\" role=\"presentation\">based on<\/span> <span dir=\"ltr\" role=\"presentation\">sacrificial bioprinting, i.e., the use of <\/span><span dir=\"ltr\" role=\"presentation\">two different bioinks to create<\/span> <span dir=\"ltr\" role=\"presentation\">hollow<\/span> <span dir=\"ltr\" role=\"presentation\">structure<\/span><span dir=\"ltr\" role=\"presentation\">s<\/span> <span dir=\"ltr\" role=\"presentation\">embedded <\/span><span dir=\"ltr\" role=\"presentation\">in<\/span> <span dir=\"ltr\" role=\"presentation\">a<\/span> <span dir=\"ltr\" role=\"presentation\">cell<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">laden matrix. With this method, we<\/span> <span dir=\"ltr\" role=\"presentation\">succeeded in <\/span><span dir=\"ltr\" role=\"presentation\">fabricat<\/span><span dir=\"ltr\" role=\"presentation\">ing<\/span> <span dir=\"ltr\" role=\"presentation\">customizable endothelialized perfusable 3D <\/span><span dir=\"ltr\" role=\"presentation\">constructs<\/span> <span dir=\"ltr\" role=\"presentation\">sustaining<\/span> <span dir=\"ltr\" role=\"presentation\">cell<\/span> <span dir=\"ltr\" role=\"presentation\">culture for<\/span> <span dir=\"ltr\" role=\"presentation\">ov<\/span><span dir=\"ltr\" role=\"presentation\">er<\/span> <span dir=\"ltr\" role=\"presentation\">two weeks under <\/span><span dir=\"ltr\" role=\"presentation\">continuous perfusion.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-512 size-full\" src=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg\" alt=\"\" width=\"919\" height=\"596\" srcset=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg 919w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2-300x195.jpg 300w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2-768x498.jpg 768w\" sizes=\"auto, (max-width: 919px) 100vw, 919px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-515 size-full\" src=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/12541878-80ab-443d-8fa3-949cff6eef5c.jpg\" alt=\"\" width=\"1024\" height=\"519\" srcset=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/12541878-80ab-443d-8fa3-949cff6eef5c.jpg 1024w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/12541878-80ab-443d-8fa3-949cff6eef5c-300x152.jpg 300w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/12541878-80ab-443d-8fa3-949cff6eef5c-768x389.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-537 size-large\" src=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2023\/01\/64b07cc3-21e6-4e90-a7e4-35b4523378a5-1024x763.jpg\" alt=\"\" width=\"1024\" height=\"763\" srcset=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2023\/01\/64b07cc3-21e6-4e90-a7e4-35b4523378a5-1024x763.jpg 1024w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2023\/01\/64b07cc3-21e6-4e90-a7e4-35b4523378a5-300x224.jpg 300w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2023\/01\/64b07cc3-21e6-4e90-a7e4-35b4523378a5-768x572.jpg 768w, https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2023\/01\/64b07cc3-21e6-4e90-a7e4-35b4523378a5.jpg 1208w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3D bioprinting is an additive manufacturing process that involves the use of biomaterials, cells and biomolecules to fabricate three-dimensional structures that mimic the characteristics and function of specific natural tissues. The bioprinting process starts with modeling the three-dimensional constructs, creating a digital model equipped with a set of instructions for fabricating layer-by-layer the desired structure.&hellip; <br \/> <a class=\"read-more\" href=\"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482\">Leggi tutto<\/a><\/p>\n","protected":false},"author":81,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"folder":[],"class_list":["post-482","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>3D Bioprinting to mimic human body - BIAMET Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"3D Bioprinting to mimic human body - BIAMET Laboratory\" \/>\n<meta property=\"og:description\" content=\"3D bioprinting is an additive manufacturing process that involves the use of biomaterials, cells and biomolecules to fabricate three-dimensional structures that mimic the characteristics and function of specific natural tissues. The bioprinting process starts with modeling the three-dimensional constructs, creating a digital model equipped with a set of instructions for fabricating layer-by-layer the desired structure.&hellip; Leggi tutto\" \/>\n<meta property=\"og:url\" content=\"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482\" \/>\n<meta property=\"og:site_name\" content=\"BIAMET Laboratory\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-27T11:10:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482\",\"url\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482\",\"name\":\"3D Bioprinting to mimic human body - BIAMET Laboratory\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/wp-content\\\/uploads\\\/sites\\\/26\\\/2022\\\/12\\\/3D_2.jpg\",\"datePublished\":\"2022-12-22T16:08:06+00:00\",\"dateModified\":\"2023-01-27T11:10:48+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482#breadcrumb\"},\"inLanguage\":\"it-IT\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482#primaryimage\",\"url\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/wp-content\\\/uploads\\\/sites\\\/26\\\/2022\\\/12\\\/3D_2.jpg\",\"contentUrl\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/wp-content\\\/uploads\\\/sites\\\/26\\\/2022\\\/12\\\/3D_2.jpg\",\"width\":919,\"height\":596},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?page_id=482#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"3D Bioprinting to mimic human body\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/#website\",\"url\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/\",\"name\":\"BIAMET Laboratory\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"it-IT\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/#organization\",\"name\":\"Universit\u00e0 degli studi di Padova\",\"url\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/wp-content\\\/uploads\\\/sites\\\/26\\\/2022\\\/12\\\/Immagine2.jpg\",\"contentUrl\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/wp-content\\\/uploads\\\/sites\\\/26\\\/2022\\\/12\\\/Immagine2.jpg\",\"width\":1901,\"height\":394,\"caption\":\"Universit\u00e0 degli studi di Padova\"},\"image\":{\"@id\":\"https:\\\/\\\/research.dii.unipd.it\\\/biamet\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"3D Bioprinting to mimic human body - BIAMET Laboratory","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482","og_locale":"it_IT","og_type":"article","og_title":"3D Bioprinting to mimic human body - BIAMET Laboratory","og_description":"3D bioprinting is an additive manufacturing process that involves the use of biomaterials, cells and biomolecules to fabricate three-dimensional structures that mimic the characteristics and function of specific natural tissues. The bioprinting process starts with modeling the three-dimensional constructs, creating a digital model equipped with a set of instructions for fabricating layer-by-layer the desired structure.&hellip; Leggi tutto","og_url":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482","og_site_name":"BIAMET Laboratory","article_modified_time":"2023-01-27T11:10:48+00:00","og_image":[{"url":"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Tempo di lettura stimato":"3 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482","url":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482","name":"3D Bioprinting to mimic human body - BIAMET Laboratory","isPartOf":{"@id":"https:\/\/research.dii.unipd.it\/biamet\/#website"},"primaryImageOfPage":{"@id":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482#primaryimage"},"image":{"@id":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482#primaryimage"},"thumbnailUrl":"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg","datePublished":"2022-12-22T16:08:06+00:00","dateModified":"2023-01-27T11:10:48+00:00","breadcrumb":{"@id":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482#breadcrumb"},"inLanguage":"it-IT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/research.dii.unipd.it\/biamet\/?page_id=482"]}]},{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482#primaryimage","url":"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg","contentUrl":"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/3D_2.jpg","width":919,"height":596},{"@type":"BreadcrumbList","@id":"https:\/\/research.dii.unipd.it\/biamet\/?page_id=482#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/research.dii.unipd.it\/biamet\/"},{"@type":"ListItem","position":2,"name":"3D Bioprinting to mimic human body"}]},{"@type":"WebSite","@id":"https:\/\/research.dii.unipd.it\/biamet\/#website","url":"https:\/\/research.dii.unipd.it\/biamet\/","name":"BIAMET Laboratory","description":"","publisher":{"@id":"https:\/\/research.dii.unipd.it\/biamet\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/research.dii.unipd.it\/biamet\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"it-IT"},{"@type":"Organization","@id":"https:\/\/research.dii.unipd.it\/biamet\/#organization","name":"Universit\u00e0 degli studi di Padova","url":"https:\/\/research.dii.unipd.it\/biamet\/","logo":{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/research.dii.unipd.it\/biamet\/#\/schema\/logo\/image\/","url":"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/Immagine2.jpg","contentUrl":"https:\/\/research.dii.unipd.it\/biamet\/wp-content\/uploads\/sites\/26\/2022\/12\/Immagine2.jpg","width":1901,"height":394,"caption":"Universit\u00e0 degli studi di Padova"},"image":{"@id":"https:\/\/research.dii.unipd.it\/biamet\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=\/wp\/v2\/pages\/482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=\/wp\/v2\/users\/81"}],"replies":[{"embeddable":true,"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=482"}],"version-history":[{"count":10,"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=\/wp\/v2\/pages\/482\/revisions"}],"predecessor-version":[{"id":510,"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=\/wp\/v2\/pages\/482\/revisions\/510"}],"wp:attachment":[{"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=482"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/research.dii.unipd.it\/biamet\/index.php?rest_route=%2Fwp%2Fv2%2Ffolder&post=482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}